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It's Finally Here! The Wellness Club Website Has Had A Make-Over!

09/27/07

This Week In HealthBeat News:

  • It's Finally Here! The Wellness Club Website Has Had A Make-Over!
  • Optimist or Pessimist -- Does It Really Matter To Health?

  • What I Admire About My European Patients
  • A Lesson In How To Get Your Research Funded (And Your Salary Paid): A Look Behind The Scenes
  • Got Cancer? Two Reasons You Have My Deep Sympathy
  • We Get Questions: What Oil To Cook With?
  • Laughter is Good Medicine: Remembering Red Skelton

It's Finally Here! The Wellness Club Website Has Had A Make-Over!

The Wellness Club has been serving you on-line since 1994, and we think that this new website is the best we have ever looked! With a cheery new look, a new shopping cart, new features, and new articles along with all the carefully researched, scientifically accurate information you have come to expect from us, we think that you will think it's a winner too!

Finding the new website is easy - just go to www.DrMyattsWellnessClub.com as you always have.

One of our great new features is an improved search - if there is something you are looking for, or something you can't find, try typing it into the search box at the upper right of the page. Products or information, if it is within The Wellness Club website the search will probably find it for you!

Using the new shopping cart is also be easy - those of you who have ordered from us before will most likely already have an "account" set up that you can "login" to. We have been working hard to get as much of our customers information as we can moved over to the new shopping cart - you may login using your email address, and your password should be your membership number. If your membership number doesn't work as a password, you can always click on the "I Forgot My Password" link, and your password will be e-mailed to you. If the cart does not recognize you by your e-mail address, you may have begun using a new address but not told us, so we may have your old address in the system - try the old address.

If you are having problems, please call me, Nurse Mark, at 1-800-376-9288 and we'll get things worked out for you.

If you are or have been a Wellness Club Member and cannot get logged-in PLEASE call Nurse Mark for help before creating a whole new account! We want you to keep your familiar membership number and your discounts!

Once you are logged in, please make sure that all the information is correct: Name, billing address, shipping address, phone number, e-mail address. This is also a good time to change your password if you wish. (Please remember though, if you like to call in your orders sometimes, that Nurse Mark will need to know what your password is so that we can use the shopping cart system to place the order on your behalf - in this case, your membership number may be the best password!)

The new cart will do some cool things too: it will calculate your member discount, figure in your free shipping, and remember your credit card number for subsequent orders - all with complete security.

Optimist or Pessimist -- Does It Really Matter To Health?

By Dr. Dana Myatt

Your outlook on life influences your health, as I'm sure you've heard unless you've been living in a cave for the past two decades. But do you really need to keep your rose colored glasses permanently in place, or is it the absence of pessimism that matters most?

Here's good news for those who don't feel like they can simply be "optimistic at will." You don't need to be an optimist to experience health benefits. It looks like simply not being a pessimist is good enough. If you're a realist like I am, that's good enough.

One medical school professor calling me "terminally optimistic" to the contrary, I actually consider myself a dyed-in-the-wool realist. Maybe it started with my mother who taught me to "Remember, Honey, no matter how bad things get, it could always be worse." Thanks, Mom.

She was right, of course. That's where the seeds of my "realism" were surely planted.

So, what's the difference between a realist and a pessimist? Or an optimist, for that matter?

Two days ago I was sitting on my deck with a friend, enjoying one of the first true Fall mornings we've had. The nights are cooler now, and leaves have the first hint of gold. There's no doubt that Fall is in the air.

On this beautiful Fall morning, we were enjoying a lovely temperature (about 68), with not a single cloud in a crystal-blue sky. There was barely even a breeze to disturb the solitude. Chickadees were chirping feverishly for a spot at the fountain, and an occasional cow moo'ed in the distance. "Pastoral" is the word that came to my mind, and it was lovely. I remarked about the beauty of this first Fall day to my friend.

To my suprise, she lamented Fall coming because it meant that Winter was not far behind. Even the amazingly clear blue sky and perfect temperature failed to delight her.

I had to laugh. After all, Winter has been following Fall in these parts for as long as I've lived here. According to the locals, it's been that way for decades before that, probably centuries. And yes, we can have some freezing-cold days in the Winter, global warming notwithstanding.

Winter follows Fall. Like death and taxes, some things are inevitable. Why would I let the thought of a future blustery Winter day interfere with my enjoyment of an incredible present-moment Fall morning? After all, none of us knows if we'll even see tomorrow. (The Realist in me). I try to embrace every lovely moment I can, and milk it for all it's worth. But that's being Real, not optimistic.

Most psych/health studies show that it's the absence of pessimism, not the presence of optimism, that has a profound influence on health.

So, next time you read a study about how pessimists don't fare as healthfully as non-pessimists, don't believe you have to strain to see the world through rose-colored spectacles. Just "Get Real," and that's good enough.

References:

1.) Optimism, pessimism, and change of psychological well-being in cancer. Psychol Health Med. 2007 Aug;12(4):421-32. patients.
2.) Effects of optimism, pessimism, and trait anxiety on ambulatory blood pressure and mood during everyday life. J Pers Soc Psychol. 1999 Jan;76(1):104-13.
3.) Pessimism as a predictor of emotional morbidity one year following breast cancer surgery. Psychooncology. 2004 May;13(5):309-20.

What I Admire About My European Patients

By Dr. Dana Myatt

As many of you know, my patients are spread throughout the world. That's one of the advantages of "seeing" patients via telephone conference and the internet --- they don't have to be in my hometown, or I in theirs, for us to work together.

As a result of this global practice, I have a number of European patients in my care. I also have patients who grew up in Europe but now live in the states. Many are Americans, but they still have a distinct "European trait" about them that I truly admire.

I gave an answer last week to a patient of mine who inquired about a "new study" he'd read on the internet relating to prostate cancer. (See "Rooster's Crowing..."). Early-on, I had warned him about trying to "make something" of every abstract he read, and assured him that he'd have to get up very early to see a medical study I and my team didn't already know about. But he did it anyway: he emailed and asked me to explain a study he'd seen.

So I did, and let the rest of you read my answer (or at least part of it). The part you didn't see was where I admonished this patient that if I had to take an hour to interpret every study's abstract he read that he couldn't understand, I'd have to put him "on the clock."

Here's where that "European trait" I admire comes in.

This patient is from the UK. He wrote back thanking me profusely for my answer, noting that it was a great response to read and yes, "above the call of duty" and in future, he didn't mind being billed for such answers. It was a nice letter.

But I've given similar responses (requiring similar amounts of time and energy) to American patients, and the reply is often not so heart-warming. "Oooh, you didn't have to be so harsh." Or worse, they get mad at me for being "unfeeling." In other words, don't "call it like you see it" or tell it to me straight, you might hurt my "inner child."

Seems the "nurture your inner child" phenomenon is highly American. In Europe, you keep a stiff upper lip. And I like it. Too many people are far too soft on themselves --- and won't accept any stern guidance from anyone else --- much to their detriment.

People who are willing to listen to critique, even if it stings a bit, seem to fare better when it comes to their health. At least that's my observation, and it ties in with this week's other article on pessimism vs. optimism.

My recommendation? Enough with the "inner child" movement! Nurture your inner grown up. Be willing to listen and consider critique, even when it hurts. Be willing to be dedicated and stern with yourself, especially when it comes to your mental and physical health. Your "inner grown up" might be the very thing that will save you --- or at least improve you.

A Lesson In How To Get Your Research Funded (And Your Salary Paid): A Look Behind The Scenes

By Nurse Mark

As we have pointed out in recent HealthBeat articles, our patients tend to be a bright and curious lot - and none are more passionately interested in their condition and treatment than our prostate cancer patients. We get plenty of notes asking us if we have seen this research or that, and plenty more asking us if we are using the latest, hippest treatments or supplements. Here is a recent example:

Hello Dr Myatt,

The abstract below prompts me to ask whether the supplement which you have supplied is the B-DIM. My guess is probably not but I may be pleasantly surprised. If not, what might you do to obtain said B-DIM?

In hope and with best wishes,
Graham

And Graham refers to the following research article, found on the internet:

Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells.  Urologic Oncology. 25(2):180-181, Jennifer J. Westendorf, Luke Hoeppner

which concludes with the sentence:

"These observations provide a rationale for devising novel therapeutic approaches for the treatment of hormone-sensitive, but more importantly, hormone-refractory prostate cancer by using B-DIM alone or in combination with other therapeutics." (Yes, these articles really are as dry as this...!)

Dr. Myatt replied:

Hi Graham:

No commercially available products of bis-DIM are available (as near as I can find). Remember, this study just came out in July.

However, I smell a drug company rat behind this. Remember, numerous studies --- the references I previously sent to you --- already found a great and positive effect on prostate cancer using the non-bis form of DIM. That means you don't need the bis-form to get the expected results.

Drug companies like to find a "tweak" (small variation) to a natural substance so they can patent it as their unique drug, hence my comment about "I smell a drug company...." The unpatentable form of DIM has been well-studied and works, (so do Mother Nature's cruciferous vegetables --- 'WAY unpatentable) but any of these will be harder to get drug approval for.

The DIM I sent you is the kind used in multitudinous other positive-outcome studies. It is not the bis-form reported in this one study, which again, I do not believe is commercially available yet, at least not in USA. One study does not "proof" make. We'll see if any other studies verify that the bis-DIM is truly more absorbable. Until then, don't stop taking your DIM's!

In Health,
Dr. Myatt

And Further to Dr. Myatt's comments, from Nurse Mark:

This study rang some bells here at my desk - beyond the veiled references in it to the possible development of "patentable" compounds... I remembered having seen this "new research" several years ago!

If we look at the earlier abstract, dated variously "Descriptive Note : Annual rept. 1 Apr 2004-31 Mar 2005" and "Report Date : APR 2006" and attributed to "Personal Author(s) : Sarkar, Fazlul H." we will see that Sarkar appears to have recycled some of the verbiage from this earlier abstract word-for-word into the more recent abstract that this reader found and sent to us.

From the earlier abstract we see:

"[...] we investigated the effects of B-DIM, a formulated DIM with greater bioavailability, on AR, Akt, and NF- B signaling in hormonesensitive LNCaP and hormone-insensitive C4-2B prostate cancer cells. We found that B-DIM significantly inhibited cell growth and induced apoptosis in both cell lines. By Akt transfection, RT-PCR, Western Blot analysis, and EMSA, we found that there could be a crosstalk between Akt, NF- B, and AR in cell signaling. Importantly, we found that B-DIM significantly inhibited Akt activation, NF- B DNA binding activity, and the expressions of AR and PSA, interrupting the crosstalk. Moreover, our confocal image study revealed that B-DIM inhibited AR nuclear translocation, leading to the down-regulation of AR target genes including PSA. These results suggest that B-DIM could inhibit cell growth and induce apoptosis partly through downregulation of AR, Akt and NF- B signaling."

And in the later abstract the authors write:

"[...] we investigated the effects of B-DIM, a formulated DIM with greater bioavailability, on AR, Akt, and nuclear factor B (NF- B) signaling in hormone-sensitive LNCaP (AR+) and hormone-insensitive C4-2B (AR+) prostate cancer cells. We found that B-DIM significantly inhibited cell proliferation and induced apoptosis in both cell lines. By Akt gene transfection, reverse transcription-PCR, Western blot analysis, and electrophoretic mobility shift assay, we found a potential crosstalk between Akt, NF- B, and AR. Importantly, B-DIM significantly inhibited Akt activation, NF- B DNA binding activity, AR phosphorylation, and the expressions of AR and prostate-specific antigen, suggesting that B-DIM could interrupt the crosstalk. Confocal studies revealed that B-DIM inhibited AR nuclear translocation, leading to the down-regulation of AR target genes. Moreover, B-DIM significantly inhibited C4-2B cell growth in a severe combined immunodeficiency-human model of experimental prostate cancer bone metastasis. These results suggest that B-DIM-induced cell proliferation inhibition and apoptosis induction are partly mediated through the down-regulation of AR, Akt, and NF- B signaling."

To my eye there are far more similarities than there are differences, despite the several years of distance between the two articles - though I'm sure that this must simply represent a continuation of the earlier research, with the researchers employing an economy of effort in reporting their newest findings which vary only slightly.

The earlier article's concluding sentence was:

"These results along with our previous findings suggest that 13C and DIM may be potent agents for the prevention and/or treatment of androgen sensitive and androgen-refractory prostate cancers."

While the later article's concluding sentence reads:

"These observations provide a rationale for devising novel therapeutic approaches for the treatment of hormone-sensitive, but more importantly, hormone-refractory prostate cancer by using B-DIM alone or in combination with other therapeutics."

In neither abstract does the author minimize the efficacy of conventional forms of 13C or DIM - but it would appear that the author has, in the latter abstract, come to grips with the reality of obtaining funding for continued research: to wit, the big bucks flow from the pharmaceutical giants who are not the least interested in anything that cannot be afforded the profit protection of patentability. It would appear that B-DIM may just satisfy that requirement, hence the shift of focus from traditional forms of DIM to the "formulated DIM" which ostensibly has "greater bio availability" and by inference must be better. Even if it is not significantly "better" clinically, it will certainly be "better" from a business standpoint, as it will be patentable and profitable - and therefore worthy of the investment of research dollars.

This is not meant to belittle this research - for it is indeed important and valuable research. It is meant instead to show how a savvy researcher will "adjust" his research to suit his intended audience. The big money is not in the science of it, or in "doing good" for cancer sufferers - the real money for research comes from Big Pharma, and they are only going to be interested in funding research if it will "pay off" for them - hence this smart researcher's subtle switch from using ol' fashioned DIM to "B-DIM, a formulated DIM with greater bioavailability".

Got Cancer? Two Reasons You Have My Deep Sympathy

By Dr. Dana Myatt

I feel sorry for my cancer patients and not just because of the diagnosis. In terms of "outcomes," even advanced cancers are usually controllable when treated correctly. I've had 19 years of medical practice and many patients still alive and well 10+ years after a "two months to live" diagnosis to vouch for this.

No, it's not the diagnosis itself that makes me feel bad for cancer patients. It's what happens to friends, family and even total strangers when they hear someone has "the 'C' word." Apparently totally sane people get absolutely stupid and make the cancer patient bear the brunt of their foolishness.

Here are two big reasons my heart goes out to cancer patients:

1.) "Everybody is an Expert." I don't know why this applies to cancer and not other equally serious diseases, but it seems that Aunt Martha, the dog-groomer next door, your car mechanic, the clerk at the health food store and EVERY SECOND PERSON you bump into is a "cancer expert" when they hear of your diagnosis.

People with not one single day of medical training magically become authorities when they hear you have cancer. They know which chemotherapy you should have (or that you should absolutely avoid any conventional treatment altogether), what diet you should be on (an "alkalinizing" diet is a popular recommendation among people who know absolutely nothing of what they're talking about), juice fasting, blah, blah, blah.

I don't know what to tell you if you have cancer and are on the receiving end such blatant stupidity. Maybe it's better not to announce your diagnosis to the entire world, only close friends and family? (Even then, you'll still encounter a lot of "experts"). You can tell them you're working with a fine team of REAL medical experts, but that usually doesn't slow them down one iota.

If it were me, I think I'd say something like, "I appreciate your concern, but I make my treatment decisions with a top-notch team of medical experts including a naturopathic physician who specializes in cancer treatment (that would be ME), and I really don't feel I need any additional input at this time. Can we talk about something else?"

Just a thought.

2.) The "I had an uncle who...." cancer stories. (I got this just yesterday from a patient, and it's worth passing on).

When the hoi polloi hear you've got cancer, they often jump in with a story about a friend or family member who suffered and died from the disease.

HELLO? What the He#! are they thinking?

You don't need stories of people who didn't make it --- you need stories about all the ones who DID make it. (I've got lots of these, by the way. My favorites are the "advanced cancer" patients who buck the odds for years or decades...).

But success stories are usually not what you're going to get. It's truly mind-boggling how stupid even smart people can get when confronted with an acquaintance (or total stranger!) who has cancer.

What would I do? Probably look at them like they just got off a spaceship from Mars and say something like, "Gee, thanks for sharing a 'cancer death story,' but I'd prefer to hear a cancer success story. In fact, that's the only kind of cancer story my naturopathic cancer doctor advises me to listen to. Do you have one of those?"

Pause for a moment (believe, me, this will be a pregnant pause), and wait for their reply.

Oh, and don't feel bad if they don't have a "success story." When people are treated with conventional therapy alone, the treatment usually kills them LONG before the disease would have, and that's the only story most people are familiar with.

I'm sorry you'll be dealing with human stupidity along with your diagnosis, but it's a fact of life. Like everything else in life, you'll have to deal with it. So let's do this:

Write and tell me what YOU would say in each of the above scenarios. We'll post the possible retorts in an upcoming edition of HealthBeat.

We Get Questions: What Oil To Cook With?

By Dr. Myatt and Nurse Mark

It seems that there are few subjects surrounded by more confusion, obfuscation, and even outright disinformation and lies than the subject of oil - the edible kind, that is. This was the subject of a HealthBeat article a while back: Saturated Fats: Another Big Fat Lie  In it I told the story of the villification of saturated fats, including a wonderful oil, Coconut oil.

This question came in recently from a reader who obviously hasn't seen that article...

Hi Doc!
Your reports are always good to read and informative. I will be calling this week to order supplements as soon as I check which I am low on. I wanted to ask you a question regarding oils. I have read that Omega 3's are good and healthful, but several articles have stated that Omega 9's are just the opposite and even Omega 6's are not that desirable. I read your last article about cooking with oils and how they are changed in the process. I must admit that I have used olive oil to cook with for quite a while now, actually since my heart attack in 2004 because I keep reading how good they are and how the Mediterranean diet relies so heavily on it. If this oil changes characteristics when heated and is not advised, what oil can I cook with?
I have recently purchased grape seed oil at a local supermarket and have been using that. Is this OK?
Thanks for your feedback!
truly
Andrew

And Dr. Myatt replies:

Hi Andy:

Omega-9 oils are "neutral" when uncooked, but not good to cook with because they are all polyunsatured (PUFA) oils. (Omega-3's, Omega-6's and Omega-9's are all "PUFA's" and should not be heated).

Saturated fats do not go "bad" with heating. Pure coconut oil is best for cooking. Saturated fats, especially coconut oil but also lard, have been wrongly maligned as a cause of atherosclerosis. This is a bogus claim - your cell walls are largely made of saturated fats! And "sat fats" such as coconut oil don't turn into anything nasty when heated, even to high temperatures. Use flax oil and olive oil for salad dressing and the like (and the flax is a "health food"), use coconut oil for frying.

We now offer organic virgin coconut oil in 14 ounces jars for this purpose

Hope this clears things up for you!

In Health,
Dr. Myatt

Laughter is Good Medicine: Remembering Red Skelton

A reader recently sent us a forwarded email which contained what were purported to be quotes by the late, great Red Skelton. Now, I was a big fan of Red, and Dr. Myatt was not only a fan but had the pleasure of serving Mr. Skelton many times when she was working as a waitress to finance her way through medical school - we both remember him as a gentle man with never an unkind word for anyone. Some of the quotes attributed to him seemed a little harsh, so, like everything here at the Wellness Club, this got researched too. What follows is the most accurate I can find - possibly not perfectly accurate, but still certain to bring a smile to your face as you remember "America's Clown."

"All men make mistakes, but married men find out about them sooner."  Red Skelton

RED SKELTON'S TIPS FOR A HAPPY MARRIAGE

1. Two times a week, we go to a nice restaurant, have a little beverage, then comes good food and companionship. She goes on Tuesdays, I go on Fridays.

2. We also sleep in separate beds. Hers is in Ontario and mine is in Tucson.

3. I take my wife everywhere, but she keeps finding her way back.

4. I asked my wife where she wanted to go for our anniversary. "Somewhere I haven't been in a long time!" she said. So I suggested the kitchen.

5. We always hold hands. If I let go, she shops.

6. She has an electric blender, electric toaster and electric bread maker.  Then she said "There are too many gadgets and no place to sit down!" So I bought her an electric chair.

7. My wife told me the car wasn't running well because there is water in the carburetor. I asked where the car was, she told me "In the Lake."

8. She got a mudpack and looked great for two days. Then the mud fell off.

9. She ran after the garbage truck, yelling "Am I too late for the garbage?" The driver said "No, jump in!"

10. Remember. Marriage is the number one cause of divorce.

11. Statistically, 100% of all divorces start with marriage.

12. I married Miss Right. I just didn't know her first name was Always.

13. I haven't spoken to my wife in 18 months. I don't like to interrupt her.

14. The last fight was my fault. My wife asked, "What's on the TV?" I said "Dust!

Red would always end his television show in his wonderfully warm and kind voice with the words
"Good night and may God bless"

What a happy memory!

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